I. Definition:

Acanthosis nigricans is a disorder that causes light-brown-to-black, velvety, rough areas or increased skin markings usually on the back and sides of the neck. The condition can also at times occur under the arms and in the groin.

II. Cause:

Acanthosis nigricans may begin at any age.

We do not know the exact cause of this condition.

Rarely the condition is associated with an endocrine disorder or a tumor.

Acanthosis nigricans is sometimes associated with being overweight.

III. Treatment:

When acanthosis nigricans develops a medical work-up should be done to determine whether or not the patient has a gland (endocrine) disorder or a tumor.

Retin-A, 15% urea, alpha hydroxyacid, and salicylic acid are all prescriptions that may provide some improvement for this condition.

There is no cure for acanthosis nigricans. Overweight individuals usually have improvement if they lose weight. In those who have a tumor or a gland disorder, correction of the underlying problem will often cure the acanthosis nigricans.

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