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One day, Hanna Zechzer got a flier in the mail advertising an herbal pill to
help her lose weight. The testimonials said the product was "all
natural," so she thought it was safe. The leaflet sat for a
few days, then she ordered a bottle.
For a week Zechzer took three tablets a day of EZ Trim, with each
tablet containing 333 milligrams of ma huang, a natural source of
the weight-loss supplement ephedra, and 250 milligrams of guarana,
a source of natural caffeine.
Ephedra and its alkaloids are among the most popular diet supplements
in the country, but health care providers say they are also among
the most dangerous, capable of inducing adverse reactions ranging
from uncomfortably sweaty palms to heart failure and sudden death.
Zechzer, then 42, a dentist's assistant in Watertown, Wis., and
a single mother of three children, had a bit of an upset stomach
early in the week, but it was different by Thursday.
"I got real jittery, and I couldn't work," she said.
Her pulse was normal, but she took her blood pressure and found
it was 150/100. "I had a really bad headache, a tingling sensation
in my left arm and pressure in my chest."
She lowered a dentist's chair and lay down. She was very cold,
she said, "and I was thinking 'I wish someone would take care
of me.' " That was the last thing she remembered for four days
in July 1998.
According to a journal compiled by Zechzer's sisters, her co-workers
called the emergency service almost immediately, but by the time
they arrived Zechzer was in the middle of a grand mal seizure. She
was in and out of consciousness, combative and flailing her arms.
She was taken to a nearby hospital and put on life support. Doctors
found amphetamines in her blood. Was Zechzer taking speed? No, her
sisters said. But her daughters remembered the diet supplement.
Ephedra is a close chemical cousin of the illegal drug methamphetamine.
Over the weekend an ambulance moved Zechzer to St. Mary's Hospital
in Madison. Her physician started reading about ephedra. Zechzer's
heart was failing, and doctors didn't know what to do about it.
They began talking about a heart transplant. "It was a minute-to-minute
thing," Zechzer said.
By Monday, though, she was having periods of coherence, and was
writing notes in response to questions from nurses. She remembers
none of it. "My sisters kept telling me to trust them,"
she said, but she was confused and terrified.
"What happened?" reads one of her notes. "What's
the diagnosis?" "Might need a heart transplant."
"Scared a lot."
By Tuesday, she was feeling better. She learned about the ephedra,
and her rage began to grow. At 10 Tuesday evening she asked, "Can
they call that [expletive] company?" Ten days after the seizure
they removed her respirator.
In all, Zechzer was hospitalized for two weeks, but, "by the
grace of God, I had no heart damage." A lawyer is preparing
to file suit on her behalf. Distributors of EZ Trim refused to comment
on Zechzer's story.
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